Agela Cleanert MAS-Multi-function Impurity Adsorption SPE

รายละเอียด

Agela Cleanert MAS (Multi-function Impurity Adsorption SPE)

         Cleanert MAS is a simplified bio-sample preparation tool which offers multifunctional adsorption capabilities to remove interferences while the analytes are remained in the aqueous phase. Although protein precipitation is the most common method in bioanalysis, it is the fact that this method is not efficient for eliminating the matrix effect on LCMS/MS due to the present of phospholipids. However with Cleanert® MAS the phospholipids are effectively removed follows a similar procedures.

For amphoteric compounds, MAS-A should be followed by basic eluant (0.01%~1%NH3•H2O is suggested to be added in the elution solvent), while MAS-B should be followed by acidic eluant (0.02%-2% acetic acid is suggested to be added in the elution solvent). Because the acidity/basicity of most compounds are weaker than that of phospholipids which contain choline and phosphate group, elution of analytes and retention of phospholipids can be achieved by adjusting different pH value of the solvent.